Professor Ed Wild, MRCP, PhD
Editor Emeritus
London, UK
Ed is a neurologist at the National Hospital for Neurology and Neurosurgery, London, UK, and a Professor of Neurology at University College London where he is Associate Director of the Huntington’s Disease Centre. He has worked in HD research since 2005 focusing on biomarkers and clinical trials. He co-founded HDBuzz with Jeff Carroll in 2010 and was Editor-in-Chief until 2024.
Articles edited by Professor Ed Wild
- Making babies: having a family, the HD way
- Huntington’s disease therapeutics conference 2022 - Day 3
- BAC to basics: a more accurate mouse model for Huntington's disease
- Vaccines and HD
- Updates from the EHDN Plenary Meeting 2020
- Huntington’s disease therapeutics conference 2020 - Day 1
- Huntington’s disease therapeutics conference 2020 - Day 3
- Unpacking Wave's PRECISION-HD2 huntingtin-lowering trial announcement
- Could molecular handcuffs lower the protein that causes Huntington's disease?
- Details emerge of first Huntington’s disease gene therapy clinical trial
- When interrupting is good: genetic hiccups that protect against Huntington's disease
- Huntington's disease therapeutics conference 2019 - Day 3
- Huntington's disease therapeutics conference 2019 - Day 2
- Huntington's disease therapeutics conference 2019 - Day 1
- Huntington's disease goes viral as UniQure inches ahead in gene therapy race
- HDSA FAQ on the Roche/Genentech RG6042 program
- Kids sometimes get Huntington’s disease too
- Roche announces details of its 'pivotal' huntingtin-lowering study
- Disappointing news from LEGATO-HD trial of laquinimod in Huntington's disease
- HDBuzz Enrolls in Enroll-HD
- New collaboration seeks to speed Huntington's disease drug licensing
- The structure of the protein that causes Huntington's disease, revealed
- Huntington's disease therapeutics conference 2018 - day 3
- Huntington's disease therapeutics conference 2018 - day 2
- Switch off the genome editor when you’re done
- A new way of thinking about trials to prevent Huntington's disease
- Has a "wonder drug" for dementia been discovered? (Spoiler alert: no.)
- Huntington's Disease Therapeutics Conference 2017 - Day 1
- Weeding out the truth: can cannabis improve Huntington’s?
- The benefits of migration, highlighted in Huntington's disease
- A powerful message: does a toxic RNA message molecule cause harm in Huntington's disease?
- Sorry folks, the PRIDE-HD trial did NOT show that Pridopidine slows the progression of Huntington's disease
- EuroBuzz 2016: The Euro-HD Network Meeting in The Hague
- Deutetrabenazine for Huntington's disease: a positive trial but the FDA says no? Not exactly...
- Slightly long CAG repeats are more common than we thought
- Electron beam snaps best images yet of Huntington's disease protein
- Huntington's Disease Therapeutics Conference 2016 - day 3
- Huntington's Disease Therapeutics Conference 2016 - day 2
- Could a new "jaw-dropping" breakthrough help treat Huntington's Disease?
- Harnessing the power of viruses to treat Huntington's disease
- A multiple sclerosis drug that works for Huntington's disease: the real deal or too good to be true?
- Huge study reveals new 'genetic modifiers' of Huntington's disease
- Would ewe believe it? GM1, sheep and Huntington's disease
- A faulty filter? Blood vessel changes in Huntington's disease
- 2015 Huntington's Disease Therapeutics Conference: Day 3
- 2015 Huntington's Disease Therapeutics Conference: Day 2
- Can this synthetic oil help feed the brain in Huntington's disease?
- Positive results announced for re-worked tetrabenazine drug in Huntington's disease
- Turning skin cells into brain cells: a Huntington's disease research breakthrough?
- Should we worry about a huntingtin invasion?
- EuroBuzz 2014 Video, day two
- Melatonin alterations in Huntington's disease help explain trouble with sleep
- EuroBuzz 2014: day two
- Going toe-to-toe with tau: new insights into the chemical basis of Huntington’s disease
- 2CARE study of coenzyme Q for Huntington's disease ends in disappointment
- A starring role for astrocytes in Huntington's disease?
- Jumping genes: Huntington's disease protein invades brain transplants
- The brain in Huntington's disease: greater than the sum of its parts?
- Raptor announces results of cysteamine trial for Huntington's disease
- Huntington's Disease Therapeutics Conference 2014: day 2
- Prana announces results of Reach2HD trial of PBT2 for Huntington's disease
- Does high-dose creatine "slow the onset" of Huntington's Disease?
- Could a 'brain shuttle' get Huntington's disease drugs to where they're needed?
- DNA shutdown proteins in Huntington's disease: More than meets the eye
- Do dairy foods accelerate Huntington's disease?
- Buzzilia Video: Day 3
- The sweet lowdown: Huntington's disease brains use sugar differently
- Buzzilia Video: Day 1
- 'Buzzilia' from the Huntington's Disease World Congress: day 4
- 'Buzzilia' from the Huntington's Disease World Congress: day 2
- How long is too long? Rethinking the Huntington’s disease ‘gray area’
- Can sad mice help treat Huntington's disease?
- Gene silencing drug safe in ALS patients... bring on Huntington's disease trials
- Splicing with danger: a new way of thinking about the harmful Huntington's disease protein
- Proposed Huntington's disease 'biomarker' is not useful, new study suggests
- Is access to predictive genetic testing for Huntington's disease a problem?
- HD Therapeutics Conference 2013 Updates: Day 3
- HD Therapeutics Conference 2013 Updates: Day 1
- Lost in translation? New insights into the making of the Huntington's disease protein
- Simple rules for a good night's sleep in Huntington's disease
- Is a new technique set to revolutionize Huntington's disease genetic testing?
- Liver changes in Huntington's disease patients suggest more 'whole body' research needed
- The 'N17' region of huntingtin protein: an address label in Huntington's disease?
- HDBuzz Special Feature: Huntington's disease and sleep
- Gone fishing: protein network screen identifies new therapeutic targets in Huntington's disease
- Prana Biotech publishes Huntington's disease animal model data for PBT2
- 'Guard dog' proteins reveal surprising connections between Huntington's disease and other brain disorders
- Dyeing to prevent dying? Methylene blue beneficial in Huntington's disease mice
- Targeting oxidative stress in Huntington's Disease
- Of mice and men: using animal models to study Huntington's disease
- HDBuzz Prize runner-up 2012: Fruit flies, faulty connections and Huntington's disease
- HDBuzz Prize winner 2012: Deep brain stimulation for HD
- Shooting the messenger with single-stranded RNA gene silencing
- EuroBuzz Video: Day 2
- EuroBuzz News: Day 3
- EuroBuzz News: Day 1
- Lithium with a twist gets second chance for HD
- High-power brain scans reveal sodium changes in HD
- Mapping the neighborhood: huntingtin's new protein partners
- 'Induced' stem cells make exciting advances
- ASO gene silencing reaches further, lasts longer
- Exercise increases cellular recycling
- What's the connection between Huntington's Disease and cancer?
- HD Therapeutics Conference 2012 Updates: Day 3
- HD Therapeutics Conference 2012 Updates: Day 1
- Special 'brain fat' injection helps HD mice
- Could mesenchymal stem cells deliver gene silencing drugs?
- New experiments clarify the role of SIRT1 in HD - or do they?
- Gene therapy meets stem cells in liver disease success
- Chinese Huntington’s Disease Network launched
- Turning down the volume with dantrolene helps HD mice
- New antibody reveals dangerous parts of huntingtin protein
- HD World Congress 2011: a retrospective
- HD just got cilia
- Gene silencing takes a targeted step forward
- Oz Buzz Video: Day 2
- Oz Buzz Updates: Day 3
- Oz Buzz Updates: Day 1
- Stem cells and HD: past, present and future
- Cut-and-paste DNA: fixing mutations with 'genome editing'
- Re-routing the huntingtin protein inside cells
- Not all in your head: digestive problems in HD
- Meet the enemy: neutron ray reveals HD protein structure
- Improving Huntington's disease clinical trial recruitment through patient and family education
- Dimebon fails in late-stage human HD clinical trial
- FDA: further trial needed for Huntexil approval in HD
- Successful gene therapy trial in Parkinson’s Disease gives hope for HD
- What do sheep brains have to do with HD?
- Interview: CHDI Management
- CHDI Report: Day 3
- CHDI Report: Day 1
- Anti-nausea drug helps cells with the HD mutation stay healthy in a surprising way
- Memantine in HD: dose is everything
- An active lifestyle may make a difference to HD symptoms
- Getting the data out – a new scientific journal just for HD
- Dimebon: disappointing in Alzheimer’s but might work in HD
- Focused drug screening leads to improved drugs to increase the rate of cellular recycling
- Does HD cause brains to develop differently?
- Are there genetic connections between neurodegenerative diseases?
- Two large HD observational studies – COHORT and Registry – merge to create ENROLL-HD
- TRACK-HD reveals significant changes in pre-symptomatic HD mutation carriers and patients
Articles written by Professor Ed Wild
- Start here!
- PROOF-HD study of pridopidine ends with negative result
- KINECT-HD trial shows valbenazine improves involuntary movements in Huntington's disease
- Huntington's disease therapeutics conference 2021 - Day 3
- Huntington's disease therapeutics conference 2021 - Day 2
- What does COVID-19 mean for Huntington’s disease families and HD research?
- Huntington's disease therapeutics conference 2018 - day 1
- Ask the expert: Q&A on the huntingtin-lowering trial program
- Huntington's Disease Therapeutics Conference 2017 - Day 3
- Pfizer Amaryllis trial ends in disappointment: no improvement in Huntington's disease symptoms
- Huntington's Disease Therapeutics Conference 2016 - day 1
- 2015 Huntington's Disease Therapeutics Conference: Day 1
- Largest creatine clinical trial for Huntington's disease halted after 'futility' analysis
- EuroBuzz 2014 Video, day one
- EuroBuzz 2014: day three
- EuroBuzz 2014: day one
- Huntington's Disease Therapeutics Conference 2014: day 3
- Huntington's Disease Therapeutics Conference 2014: day 1
- Buzzilia Video: Day 2
- Video feature: Huntington's disease research... in space!
- 'Buzzilia' from the Huntington's Disease World Congress: day 3
- 'Buzzilia' from the Huntington's Disease World Congress: day 1
- Coming soon from the 2013 Huntington's Disease World Congress: Buzzilia!
- The 2013 HDBuzz Prize for Young Science Writers
- Does a 'rusty hinge' cause Huntington's disease?
- HD Therapeutics Conference 2013 Updates: Day 2
- Major Roche-Isis deal boosts Huntington's disease gene silencing
- No surprises in published results from HART study of Huntexil for Huntington's disease
- The University of New Orleans has NOT discovered a cure for Huntington's disease
- Prominent Huntington's disease researcher "fabricated data" in grant applications
- Calming down the immune system helps Huntington's disease mice
- Giving Huntington's disease the finger? Two teams report success for zinc-finger drugs in cells and mice
- Interview: Alice and Nancy Wexler
- Video: What’s new in Huntington's disease research 2012
- EuroBuzz Video: Day 1
- EuroBuzz News: Day 2
- Coming Soon: EuroBuzz 2012
- Does the HD mutation affect children's growth?
- Interview: CHDI's scientific team
- The HDBuzz Prize for young science writers
- Closing the care gap: new guidelines for HD care
- 2012 Therapeutics Conference: a retrospective
- Mutant yeast highlights crucial CAG-reading protein
- HD Therapeutics Conference 2012 Updates: Day 2
- Coming soon: HD Therapeutics Conference 2012
- New analysis suggests 'small' CAG length doesn't matter after all
- HDYO! Huntington's Disease Youth Organization goes live
- Double success for huntingtin RNAi gene silencing
- 2011 - a year in Huntington's disease research
- HDAC inhibitor drug protects memory in HD mice
- Huntexil hits the headlines again
- Safety trials add crucial piece to gene silencing jigsaw
- Melatonin treatment success in HD mice
- HDAC inhibitors and a possible 'blood biomarker'
- Prana Biotech's new trial of PBT2 in Huntington's disease: the lowdown
- Oz Buzz Video: Day 1
- Oz Buzz Updates: Day 2
- Stand By for Oz Buzz
- Ten golden rules for reading a scientific news story
- Protein-folding drug helps HD mice... for a while
- A back-to-front hidden message in the HD gene?
- Coming soon from the HD World Congress: Oz Buzz!
- Therapeutics conference videos now online
- Caffeine, cannabis and caution
- Huntexil update: EMA asks for further trial
- KMO inhibitor drug improves lifespan of Huntington's disease mice
- 'Floating' gene-silencing drugs into the brain with exosomes
- Chubby mice reveal the importance of the hypothalamus in Huntington's disease
- Gene silencing for HD: the story so far
- Interview: Graeme Bilbe, Global Head for Neuroscience at Novartis
- CHDI Report: Day 2
- HDBuzz takes your questions to the annual therapeutics meeting of CHDI
- Welcome to HDBuzz
- Frequently asked questions, January 2011
- Is Huntington’s disease twice as common as we thought?
- Huntexil for symptoms of Huntington's disease: where are we now?
- Minocycline: the end of the road?